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Mayo Clinic: Prediabetes May Not Explain Diabetic Polyneuropathies

The five-year study, “Impaired Glycemia and Diabetic Polyneuropathy: The OC IG Survey,” tested nearly 550 people representative of a community of older patients of Northern European extraction. Of these, 150 individuals were healthy subjects, 174 had prediabetes indicators, and 208 had newly developed type 2 diabetes. The study concluded that typical or atypical (a painful small-fiber variety) DPN was not more prevalent in prediabetics than in healthy people.

While the researchers agree that prediabetes is a precursor of type 2 diabetes, they found no evidence that it directly leads to greater prevalence of typical or atypical DPN. Attempts should be made to prevent the development of type 2 diabetes; however, considering the complications from overtreatment, the study suggests physicians should avoid treatment of prediabetes as diabetes if their intention is to prevent the development of diabetic polyneuropathy, the researchers say.

The other co-authors are Vicki Clark; Carol Overland; Jenny Davies; John Pach, M.D.; P. James B. Dyck, M.D.; Christopher Klein, M.D.; Robert Rizza, M.D.; L. Joseph Melton III, M.D.; Rickey Carter, Ph.D.; Ronald Klein, M.D.; and William Litchy, M.D.

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Mayo Clinic is a nonprofit worldwide leader in medical care, research and education for people from all walks of life. For more information, visit www.mayoclinic.com and www.mayoclinic.org/news.

Article source: http://www.sunherald.com/2012/02/21/3767637/mayo-clinic-prediabetes-may-not.html

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